Volume 10 ~ Issue 2

To see, you must close your eyes; to see beyond you must understand. As a mental process, Creativity has an abstract nature, meaning that no empiric perception is directly involved, not even words, which would bring semantic ballast. However, the relationship between the level of abstraction and the creative outcome has been largely neglected. Abstraction is not a homogenous block, but a nuanced entity. Our research considers five sublimation levels of abstraction: Paradigmatic, Pragmatic, Etiologic, Axiological and Archetypal and links them to the corresponding hierarchy of originated ideas: new Approaches, new Concepts, new Paradigms and new Formal Expressions (designs)..............

---

Author Keywords:- Kenotomy, Creativity, Ideas management, Levels of abstraction, Archetypal Perspective

---

e-ISSN: 2319-183X, p-ISSN: 2319-1821 Source Type: Journal Original Language: English
Document Type: Article Number of pages: 09

---

© Copyright 2014, All rights reserved.

A new method for aligning multiple protein sequences as well as refining methods to realign them is presented in this document. The algorithm involved in the initialization of the progressive algorithm for the alignment of sequences is computed by a radius parameter that estimates the variation between sequences; afterwards, a guide tree is created using the neighbor joining algorithm. For scoring the alignment, we introduced as metric a threshold of the number of correctly aligned symbols, and marked each sequence that reached the threshold; this metric was used to realign sequences with different thresholds in order to adjust the alignments. Our proposed method SARELI, which stands for Sequence Alignment by Radial Evaluation of Local Interactions, was previously reported to only generate the guide trees, but in this article we extended the algorithm to generate the final alignment of proteins........

---

Author Keywords:- SARELI; multiple sequence alignment; guide tree metrics; MUSCLE; protein databases.

---

e-ISSN: 2319-183X, p-ISSN: 2319-1821 Source Type: Journal Original Language: English
Document Type: Article Number of pages: 11

---

© Copyright 2014, All rights reserved.